Thrombotic Thrombocytopenic Purpura in AIDS
Alina Weisman, Geris Shehada, Ilana Oren
Depts. of Medicine A and Hematology, Rambam Medical Center and Technion School of Medicine, Haifa
Thrombotic thrombocytopenic purpura (TTP) is characterized by 5 findings: fever, neurological abnormalities, microangiopathic hemolytic anemia, severe thrombocytopenia and renal abnormalities. The syndrome occurs more often in females, usually in their 20's. Since the beginning of the current AIDS epidemic, there have been reports of an association between HIV infection and TTP. We describe a 31-year-old man with HIV who developed TTP, and review the literature.