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עמוד בית
Sun, 24.11.24

Reviews


Neuroprotection in Progressive Brain Disorders

Click on the icon on the upper right hand side for the article by Ruth Djaldetti, MD, Nirit Lev, MD and Eldad Melamed, MD.
IMAJ 2003: 5: August: 576-580
Abstract

Progressive neurodegenerative disorders share common mechanisms of cell death, and in all likelihood multiple factors are involved in every disease. Therefore, several neuroprotective agents are being investigated with the purpose of slowing or preventing further deterioration of cell loss. These include experimental animal and clinical studies on the neuroprotective effects of caspase inhibitors, antioxitands, glutamate antagonists, anti-inflammatory agents and trophic factors in several neurodegenerative diseases. At present there is limited clinical evidence for direct neuroprotective effects against these diseases, but much effort is being invested in research on novel technologies and compounds.

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