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עמוד בית
Mon, 07.04.25

The Mosaic of Autoimmunity

IMAJ | volume 10

Journal 1, January 2008
pages: 43-44

Atherosclerotic Cardiovascular Disease in Systemic Lupus Erythematosus: the Beer Sheva Experience

    Summary

     

    Atherosclerotic disease is common in systemic lupus erythematosus and is the result of multiple pathogenic mechanisms that include traditional risk factors as well as SLE[1]-related factors. Endothelial dysfunction and arterial stiffness contribute significantly to the atherogenic process. Dobutamine stress echocardiogram has not been shown to detect subclinical coronary artery disease; however the high percentage of left ventricular outflow gradient requires further evaluation and follows-up studies.



    [1] SLE = systemic lupus erythematosus

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