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    עמוד בית
    Sat, 12.04.25

    CASE COMMUNICATION

    IMAJ | volume 25

    Journal 6, June 2023
    pages: 443-444

    Small Choroidal Melanoma Associated with Choroidal Neovascularization

    1 Department of Ophthalmology, Samson Assuta Ashdod University Hospital, Ashdod, Israel 2 Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Israel 3 Department of Pediatrics, Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel 4 Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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    Summary

    The prevalence of choroidal nevi associated with choroidal neovascular membrane (CNV) is estimated to range between 0.58% and 8.6% [1]. The pathogenesis of CNV is not completely understood. Researchers have suggested that damage caused to the choroid capillaries above the nevi affects the overlying retinal pigment epithelium and triggers production of angiogenic factors that, in turn, cause the development of CNV [2,3]. Hypoxia and inflammation may be involved in the process. Data have been inconsistent with both theories [4].

    Full article (PDF)
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