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עמוד בית
Fri, 22.11.24

Original Articles

IMAJ | volume 12

Journal 5, May 2010
pages: 277-279

Age-Related Immunoglobulin G Seroprevalence of Human Parvovirus B-19 in Israeli Children

    Summary

    Background:

    Human parvovirus B19 is a global and common infectious pathogen in humans, primarily in children.


    Objectives:

    To assess the immunoglobulin G seroprevalence of B19 in children in Israel.

    Methods:

    Overall, 128 previously healthy children (1.5–17 years old) hospitalized for various diseases other than acute human parvovirus B19 infection were assessed for IgG[1] to the virus by enzyme-linked immunosorbent assay. 

    Results:

    The IgG seroprevalence increased from 22% in children aged 1.5–9 years to 52% in older children (P = 0.001).

    Conclusions:

    Our data suggest that most acute parvovirus B19 infections in Israel occur in the early school years, and that by 18 years of age 50% of Israeli children have been infected by the virus.

    [1] IgG = immunoglobulin G

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