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עמוד בית
Tue, 15.04.25

Original Articles

IMAJ | volume

Journal 9, September 2005
pages: 575-577

Autoimmune Phenomena Following Prostatectomy

    Summary

     Background: Benign prostatic hypertrophy is the most common benign tumor in males, resulting in prostatectomy in 20–30% of men who live to the age of 80. There are no data on the association of prostatectomy with autoimmune phenomena in the English-language medical literature.

    Objectives: To report our experience with three patients who developed autoimmune disease following prostatectomy.

    Patients: Three patients presented with autoimmune phenomenon soon after a prostectomy for BPH[1] or prostatic carcinoma: one had clinically diagnosed temporal arteritis, one had leukocytoclastic vasculitis, and the third patient developed sensory Guillian-Barré syndrome following prostatectomy.

    Conclusions: In view of the temporal association between the removal of the prostate gland and the autoimmune process, combined with previously known immunohistologic features of BPH, a cause-effect relationship probably exists.

    ________________

    [1] BPH = benign prostatic hypertrophy

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