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עמוד בית
Wed, 09.04.25

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June 2012
I. Zvidi, A. Geller, E. Gal, S. Morgenstern, Y. Niv and R. Dickman
May 2007
N. Yarom, N. Dagon, E. Shinar and M. Gorsky

Background: Oral lichen planus is a cell-mediated immune condition of unknown etiology. A possible association of OLP[1] with hepatitis C virus infection has been documented in specific populations. However, no such possible association has been studied in Israel.

Objectives: To assess the prevalence of HCV[2] antibodies among patients with OLP in Israel.

Methods: The prevalence of HCV seropositivity was studied in OLP patients (n=62) and compared with that of a control group (n=65) and with the prevalence among healthy volunteer blood donors (n=225,452) as representatives of the general population.

Results: The prevalence of HCV, as detected by the presence of anti-HCV antibodies screened by enzyme-linked immunosorbent assay, and confirmed by recombinant immunoblot assay, was 4.8%, 1.5% and 0.1%, respectively. HCV seropositivity in the OLP patients was significantly higher than in the healthy blood donors (P < 0.001).

Conclusions: A possible association between OLP and HCV is suggested. Therefore, screening OLP patients for antibodies to HCV is recommended.







[1] OLP = oral lichen planus

[2] HCV = hepatitis C virus


May 2002
Aneta Lazarov, MD, Keren Moss, MD, Natalie Plosk, MD, Mario Cordoba, MD and Liliana Baitelman, Pharm
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